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Antiamyloid Gantenerumab Disappoints in Phase 3 Trials

The antiamyloid monoclonal antibody gantenerumab led to a lower amyloid plaque burden but no clear cognitive benefit in early Alzheimer s disease in twin pivotal trials.

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Gantenerumab Does Not Slow Clinical Decline in Early Alzheimer Disease

The use of gantenerumab leads to lower amyloid plaque burden at 116 weeks, but is not associated with slower clinical decline among patients with early Alzheimer disease.

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Gantenerumab Does Not Slow Clinical Decline in Early Alzheimer Disease

Gantenerumab leads to lower amyloid plaque burden, but is not associated with slower clinical decline with early Alzheimer disease.

Randallj batemanWashington university school of medicineHealthday newsNew england journalWashington university schoolClinical dementia rating scale sum

Gantenerumab Does Not Slow Clinical Decline in Early Alzheimer Disease

Two trials show lower amyloid plaque burden with gantenerumab vs placebo at 116 weeks.

Randallj batemanWashington university school of medicineHealthday newsNew england journalWashington university schoolClinical dementia rating scale sum

Gantenerumab does not slow clinical decline in early Alzheimer disease, research finds

Gantenerumab does not slow clinical decline in early Alzheimer disease, research finds
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