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Dozens of mutations in the spike protein of the Omicron variant help it to evade all four of the classes of antibodies that can target SARS-CoV-2, according to a new MIT study. This includes antibodies generated by the immune systems of vaccinated or previously infected people, as well as most of the monoclonal antibody treatments that have been developed.

Thomas clarkNathaniel millerAlfredh casparyRahul ramanRam sasisekharanNational institutes of healthHealth sciencesAlliance for researchBiological engineeringCell reportsNational institutesReceptor binding proteinRam sasisekharan