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Horizon Therapeutics plc: New Analysis of UPLIZNA (inebilizumab-cdon) for Neuromyelitis Optica Spectrum Disorder (NMOSD) Published in Neurology Neuroimmunology & Neuroinflammation

Horizon Therapeutics plc: New Analysis of UPLIZNA (inebilizumab-cdon) for Neuromyelitis Optica Spectrum Disorder (NMOSD) Published in Neurology Neuroimmunology & Neuroinflammation published in the Annals of Neurology assesses a potential new biomarker for NMOSD attack risk, severity and treatment effects Horizon Therapeutics plc (Nasdaq: HZNP) today announced the publication of a new analysis of the pivotal Phase 2/3 N-MOmentum trial for UPLIZNA (inebilizumab-cdon), assessing the potential for reduced risk of worsening disability in those living with NMOSD. These data are published in the May issue of Neurology Neuroimmunology Neuroinflammation. UPLIZNA is the first and only FDA-approved anti-CD19 B-cell depleting humanized monoclonal antibody for the treatment of adult patients with anti-aquaporin-4 (AQP4) antibody positive NMOSD.

Quinn dinhRuth venningA neuromyelitis opticaRay gordonNeuroimmunol neuroinflammTina venturaNeuroimmunology neuroinflammationRachel vannProduct communicationsNeurology neuroimmunologyHepatitisb virusProgressive multifocal leukoencephalopathyPrescribing informationNeuromyelitis optica spectrum disorderNeuromyelitis optica spectrumNeurol neuroimmunol

Horizon Therapeutics plc: New Integrated Data and Follow-up Outcomes From Two TEPEZZA (teprotumumab-trbw) Pivotal Trials Published in The Lancet Diabetes & Endocrinology

(0) TEPEZZA significantly improved the clinical course of Thyroid Eye Disease (TED) in all patient subgroups, including those with more severe disease at baseline For patients in the follow-up period with data available at 51 weeks after the last dose of TEPEZZA, 67 percent had a proptosis response, 69 percent had a diplopia response and 83 percent had an ophthalmic composite outcome response Horizon Therapeutics plc (Nasdaq: HZNP) today announced that new pooled data from the TEPEZZA (teprotumumab-trbw) Phase 2 and Phase 3 clinical trials are now published in The Lancet Diabetes Endocrinology. The data further reinforce that TEPEZZA significantly improves proptosis (eye bulging) and diplopia (double vision) for TED patients in different subgroups, with most maintaining a long-term response. TEPEZZA the first and only medicine approved by the U.S. Food and Drug Administration (FDA) for TED is a fully human monoclonal antibody (mAb) and a targeted inhibitor of the insu

Ruth venningGeorge kahalyTina venturaRay gordonRachel vannProduct communicationsDrug administrationJohannes gutenberg university medical centerEuropean group on grave orbitopathyThyroid eye diseaseThelancet diabetesClinical activity scoreDifficult to treat patientsSaba sileThyroid eyeInflammatory bowel disease

Horizon Therapeutics: New Long-Term Data for UPLIZNA (inebilizumab-cdon) in People Living with Neuromyelitis Optica Spectrum Disorder (NMOSD)

Horizon Therapeutics: New Long-Term Data for UPLIZNA (inebilizumab-cdon) in People Living with Neuromyelitis Optica Spectrum Disorder (NMOSD) UPLIZNA continues to lower the rate of NMOSD attacks throughout the four-year open-label period (OLP) Results from NMOSD patient survey describe long and daunting journey to diagnosis Horizon Therapeutics plc (Nasdaq: HZNP) today announced new UPLIZNA (inebilizumab-cdon) data being presented at the American Academy of Neurology s 73rd Annual Meeting being held virtually April 17-22, 2021 (AAN 2021), including new, end-of-study data from the open-label extension period of the pivotal N-MOmentum trial in patients with NMOSD. UPLIZNA is the first and only FDA-approved anti-CD19 B-cell depleting humanized monoclonal antibody for the treatment of adult patients with anti-aquaporin-4 (AQP4) antibody positive NMOSD.

United statesNeuroimmunol neuroinflammQuinn dinhRuth venningTina venturaBruce creeRay gordonRachel vannProduct communicationsAmericas committee for treatmentAmerican academy of neurologyPresentation at american academy of neurologyResearch in multiple sclerosisAmerican academyAnnual meetingCalifornia san francisco weill institute

New UPLIZNA® (inebilizumab-cdon) Data in People With Neuromyelitis Optica Spectrum Disorder (NMOSD) to be Presented at the American Academy of Neurology s 73rd Annual Meeting

New UPLIZNA® (inebilizumab-cdon) Data in People With Neuromyelitis Optica Spectrum Disorder (NMOSD) to be Presented at the American Academy of Neurology s 73rd Annual Meeting
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United statesNeuroimmunol neuroinflammRuth venningTina venturaAdil javedRachel vannProduct communicationsAmerican academy of neurologyUniversity of chicagoAmerican academyAnnual meetingTreatment reducesTerm efficacy outcomesInebilizumab treatmentTerm safety outcomesInfusion reactions

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