Wildfires are thought to be increasing in severity and frequency as a result of climate change1–5. Air pollution from landscape fires can negatively affect human health4–6, but human exposure to landscape fire-sourced (LFS) air pollution has not been well characterized at the global scale7–23. Here, we estimate global daily LFS outdoor fine particulate matter (PM2.5) and surface ozone concentrations at 0.25° × 0.25° resolution during the period 2000–2019 with the help of machine learning and chemical transport models. We found that overall population-weighted average LFS PM2.5 and ozone concentrations were 2.5 µg m−3 (6.1% of all-source PM2.5) and 3.2 µg m−3 (3.6% of all-source ozone), respectively, in 2010–2019, with a slight increase for PM2.5, but not for ozone, compared with 2000–2009. Central Africa, Southeast Asia, South America and Siberia experienced the highest