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Pliant Therapeutics Announces Positive Long-Term Data from the INTEGRIS-IPF Phase 2a Trial Demonstrating Bexotegrast was Well Tolerated at 320 mg with Durable Improvement Shown in FVC and Across Multiple Measures

Bexotegrast was well tolerated up to 40 weeks of treatment with no drug-related serious adverse events Combination of bexotegrast with standard of care reduced FVC decline by 80% relative. | April 30, 2023

Lisah lancasterToby maherChristopher keenanLos angelesDrug administrationBexotegrast clinical development nextUniversity of southern californiaCorporate communicationsVanderbilt university medical centerPliant therapeutics incEuropean medicines agencyGroup demonstrated treatment effects including durable improvementsQuantitative lung fibrosisWell toleratedPercent changeCough severity visual analog scale

Pliant Therapeutics Announces Positive Long-Term Data from

Bexotegrast was well tolerated up to 40 weeks of treatment with no drug-related serious adverse events Combination of bexotegrast with standard of care.

Lisah lancasterToby maherLos angelesChristopher keenanGroup demonstrated treatment effects including durable improvementsCorporate communicationsDrug administrationVanderbilt university medical centerEuropean medicines agencyBexotegrast clinical development nextPliant therapeutics incUniversity of southern californiaQuantitative lung fibrosisWell toleratedPercent changeCough severity visual analog scale

Pliant Therapeutics Announces Positive Long-Term Data from the INTEGRIS-IPF Phase 2a Trial Demonstrating Bexotegrast was Well Tolerated at 320 mg with Durable Improvement Shown in FVC and Across Multiple Measures

Bexotegrast was well tolerated up to 40 weeks of treatment with no drug-related serious adverse events Combination of bexotegrast with standard of care reduced FVC decline by 80% relative. | April 30, 2023

Lisah lancasterChristopher keenanLos angelesToby maherDrug administrationBexotegrast clinical development nextCorporate communicationsGroup demonstrated treatment effects including durable improvementsKeck school of medicineVanderbilt university medical centerUniversity of southern californiaGlobenewswire incPliant therapeutics incEuropean medicines agencyQuantitative lung fibrosisWell tolerated

Pliant Reports Positive Data from Phase 2a Trial of Bexotegrast in Patients with IPF

Pliant Reports Positive Data from Phase 2a Trial of Bexotegrast in Patients with IPF
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Quantitative lung fibrosis

Pliant Therapeutics Announces Positive Data from the

Bexotegrast demonstrated statistically significant increase in FVC at 4, 8 and 12 weeks of treatment, outperforming lower dose groups No.

Group demonstrated strong treatmentPliant therapeutics incBexotegrast clinical development nextQuantitative lung fibrosisWell toleratedSerious adverseGroup demonstrated strong treatment effectsProfibrotic biomarkers versus placeboMixed model repeat measures analysisModified intentForced vital capacityNasdaq plrxPliant therapeutics