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Outrun emerges from stealth with $10M for E3 ligase inhibitors

Newco Outrun Therapeutics Ltd. has raised $10 million in a seed round to develop small-molecule E3 ubiquitin ligase inhibitors that prevent programmed protein degradation. The lead program targeting an E3 ligase that tags a tumor suppressor protein for destruction will now advance to preclinical development.

Scientists find new ways to convert inhibitors into degraders, paving the way for future drug discoveries

Scientists find new ways to convert inhibitors into degraders, paving the way for future drug discoveries
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Goldman Sachs Predicts at Least 45% Rally for These 2 Strong Buy Stocks — Here s Why They Have Solid Upside

Back in 1992, political wonk James Carville told Bill Clinton, “It’s the economy, stupid,” and went on to steer his candidate toward a game-changing political win. A recent note from Goldman Sachs equity strategist, David Kostin, reminds us of this – and points out that this holds the key to understanding the bullish sentiment on stocks. Simply put, investors are betting that the economy will show gains this year, and are playing stocks accordingly. Even though bond yields – which usually show a

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