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Nirmatrelvir fails to shorten COVID-19 symptoms in latest trial

A study in The New England Journal of Medicine evaluates the combination of nirmatrelvir and ritonavir against COVID-19, finding it does not significantly reduce symptom duration in vaccinated or unvaccinated adult outpatients.

New england journalUnvaccinated adult outpatientsProtease inhibitionStandard risk patients

One in five patients on Nirmatrelvir–Ritonavir experience virologic rebound, new observational study reveals

The frequency of viral rebound (VR) among acute coronavirus disease 2019 patients.

United statesAndrii vodolazhskyi shutterstockInternal medicineRebound with nirmatrelvirImage creditMass general brighamProtease inhibitionHigh risk patientsCovid 19Ars cov 2Evere acute respiratoryEvere acute respiratory syndrome

Pfizer s (PFE) PAXLOVID Receives FDA Approval for Adult Patients at High Risk of Progression to Severe COVID-19

Pfizer s (PFE) PAXLOVID Receives FDA Approval for Adult Patients at High Risk of Progression to Severe COVID-19
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United statesAlbert bourlaPfizer incDrug administrationEmergency use authorizationChief executive officerProtease inhibitionHigh risk patientsStandard risk patientsPediatric patientsNew drug application

FDA Approves Pfizer s PAXLOVID for High-Risk COVID-19 Patients

FDA Approves Pfizer s PAXLOVID for High-Risk COVID-19 Patients
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United statesAlbert bourlaDrug administrationPfizer incEmergency use authorizationChief executive officerProtease inhibitionHigh risk patientsStandard risk patientsPediatric patientsNew drug application

Pfizer s PAXLOVID™ Receives FDA Approval for Adult Patients at High Risk of Progression to Severe COVID-19

PAXLOVID is the first FDA-approved oral treatment for COVID-19; has been authorized for emergency use since December 2021 Approval is based on the totality of scientific evidence submitted,. | May 25, 2023

United statesAlbert bourlaPfizer incHuman servicesNational prescription auditAntimicrobial drugs advisory committee meetingDrug administrationCenters for diseaseUs department of healthExchange commissionLarge us health systemAdministration site conditionsGlobal fundEmergency use authorizationChief executive officerProtease inhibition