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New technology Helps in Oral Delivery of Insulin by Angela Mohan on April 6, 2021 at 3:04 PM
New insulin oral delivery system could replace traditional subcutaneous injections without the side effects caused by frequent injection.
Using prepared layers of nanosheets with insulin loaded in between layers to protect it, researchers developed gastro-resistant imine-linked-covalent organic framework nanoparticles (nCOFs) that exhibited insulin protection in the stomach as well in diabetic test subjects whose sugar levels completely returned to normal within two hours after swallowing the nanoparticles.
Led by NYUAD s Research Scientist Farah Benyettou and Program Head of Chemistry Ali Trabolsi, the findings were published in
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Credit: NYU Abu Dhabi
A revolutionary technology developed within the Trabolsi Research Group at NYU Abu Dhabi (NYUAD) could dramatically improve the well-being of diabetic patients through a simple and straightforward way: an insulin oral delivery system that could replace traditional subcutaneous injections without the side effects caused by frequent injection.
Using prepared layers of nanosheets with insulin loaded in between layers to protect it, researchers developed gastro-resistant imine-linked-covalent organic framework nanoparticles (nCOFs) that exhibited insulin protection in the stomach as well in diabetic test subjects whose sugar levels completely returned to normal within two hours after swallowing the nanoparticles. Led by NYUAD s Research Scientist Farah Benyettou and Program Head of Chemistry Ali Trabolsi, the findings were published today in