One of the hallmarks of Alzheimer’s disease is the presence of neurofibrillary tangles in the brain. These tangles, made of tau proteins, impair neurons’ ability to function normally and can cause the cells to die.A new study from MIT chemists has re
MIT chemists discovered how two types of Tau proteins, 3R and 4R, mix to form the neurofibrillary tangles seen in the brains of Alzheimer’s patients. The researchers found that the tangles can recruit any Tau protein in the brain, in a nearly random way.