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Date Time Dr Ashish Misra awarded second Perpetual IMPACT grant Dr Misra’s research focuses on improved understanding and potential treatment of atherosclerosis, a progressive disease where fatty plaque builds up in the arteries. “Atherosclerosis is the main underlying cause of cardiovascular disease (CVD), which is the leading cause of death globally,” says Dr Misra. “If we could better understand this devastating disease, we could potentially develop improved treatment methods that could save thousands of lives worldwide.” Dr Misra will build on his groundbreaking discovery in 2018 that changed our understanding of the way atherosclerosis progresses. Until then, smooth muscle cells (SMCs), found in the blood vessel wall, and their role in atherosclerotic plaque development were not much appreciated. Dr Misra revealed that in a developing plaque, very few ‘stem-cell like’ cells contribute to the plaque and convert into both disease-promoting and disease-protective

Peter thompsonAshish misraSanjay patelEileen ralstonAlma hazel eddyUniversity of western australiaDiseases groupVascular remodelling unitAssociate professor sanjay patelCoronary diseases groupProfessor peter thompsonWestern australiaMedical schoolInternal medicineEileen ralston trustபீட்டர் தாம்சன்