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Nanotechnology Now - Press Release: Dynamics of nanoparticles using a new isolated lymphatic vessel lumen perfusion system

Nanotechnology Now Home > Press > Dynamics of nanoparticles using a new isolated lymphatic vessel lumen perfusion system Schematic diagram of an intralymphatic evaluation system for nanoparticles This article was published in Nano Today, 36, Kuroda C, et al., Isolated lymphatic vessel lumen perfusion system for assessing nanomaterial movements and nanomaterial-induced responses in lymphatic vessels, online, Copyright Elsevier (2021). CREDIT Copyright © 2021 Elsevier B.V. Abstract: Nanoparticles used in drug delivery systems, bioimaging, and regenerative medicine migrate from tissues to lymphatic vessels after entering the body, so it is necessary to clarify the interaction between nanoparticles and lymphatic vessels. Although technology to observe the flow of nanoparticles through lymphatic vessels in vivo has been developed, there has been no method to evaluate the flow of nanoparticles in a more detailed and quantitative manner ex vivo. Thus, research was conducted to deve

Nordrhein westfalenNaoto saitoChika kurodaHitomi thompsonInstitute for biomedical sciencesUniversity of bonnHome press dynamicsDegree capital corpYamaguchi university faculty of medicineWave incHealth sciencesNano todayProfessor naoto saitoBiomedical sciencesYamaguchi university facultyShinshu university graduate school

New isolated lymphatic vessel lumen perfusion system to evaluate nanoparticle dynamics

New isolated lymphatic vessel lumen perfusion system to evaluate nanoparticle dynamics Nanoparticles used in drug delivery systems, bioimaging, and regenerative medicine migrate from tissues to lymphatic vessels after entering the body, so it is necessary to clarify the interaction between nanoparticles and lymphatic vessels. Although technology to observe the flow of nanoparticles through lymphatic vessels in vivo has been developed, there has been no method to evaluate the flow of nanoparticles in a more detailed and quantitative manner ex vivo. Thus, research was conducted to develop an ex vivo lymphatic vessel lumen perfusion system to determine how nanoparticles move in lymphatic vessels and how they affect the physiological movement of lymphatic vessels.

Naoto saitoChika kurodaEmily hendersonInstitute for biomedical sciencesYamaguchi university faculty of medicineHealth sciencesProfessor naoto saitoBiomedical sciencesYamaguchi university facultyShinshu university graduate schoolDrug deliveryNex vivoIn vivoசிக்கா குரோடாஎமிலி ஹென்டர்சன்நிறுவனம் க்கு உயிர் மருத்துவ அறிவியல்

Dynamics of nanoparticles using a new isolated lymphatic vessel lumen perfusion system

Dynamics of nanoparticles using a new isolated lymphatic vessel lumen perfusion system
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Kumiko ajimaTakayuki kamanakaChika kurodaHiroyuki katoKatsuya uedaHaruka ishidaToshio ohhashiKazushige yoshidaJun sasakiKaoru aokiMasanori okamotoNaoto saitoAtsushi sobajimaHisao haniuInstitute for biomedical sciencesResearch on development of new medical devices