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Scientists identify kidney genes that appear to directly affect blood pressure | Wilts and Gloucestershire Standard

Researchers have discovered 179 kidney genes that may be responsible for high blood pressure, potentially leading to new strategies for treating the condition. Known as the silent killer, high blood pressure is one of the most common diseases and remains the key risk factor for strokes and heart attacks. The condition – also known as hypertension – runs in families, but the exact mechanisms through which genes influence a person’s predisposition to hypertension is not clear. The findings published in Nature Genetics shed new light on the understanding of this. Researchers, led by Professor Maciej Tomaszewski at the University of Manchester, characterised how information inherited in DNA translates into genetic predisposition to high blood pressure through changes in activity of certain kidney genes.

Scientists identify kidney genes that appear to directly affect blood pressure

Researchers have discovered 179 kidney genes that may be responsible for high blood pressure, potentially leading to new strategies for treating the condition. Known as the silent killer, high blood pressure is one of the most common diseases and remains the key risk factor for strokes and heart attacks. The condition – also known as hypertension – runs in families, but the exact mechanisms through which genes influence a person’s predisposition to hypertension is not clear. The findings published in Nature Genetics shed new light on the understanding of this. Researchers, led by Professor Maciej Tomaszewski at the University of Manchester, characterised how information inherited in DNA translates into genetic predisposition to high blood pressure through changes in activity of certain kidney genes.

Causal blood pressure genes found in human kidney

Date Time ‘Causal’ blood pressure genes found in human kidney An international team of scientists led by The University of Manchester have discovered 179 kidney genes responsible for high blood pressure. High blood pressure, known as “silent killer”, is one of the most common human diseases and remains the key risk factor for strokes and heart attacks. High blood pressure – or hypertension- runs in families but the exact mechanisms through which genes influence individuals’ predisposition to hypertension is not clear. The discoveries published in Nature Genetics, one of the world’s leading journals, shed new light on our understanding of genetic predisposition to high blood pressure.

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