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CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

Max delbrChristine kocksKlaus rajewskyXun liHelmholtz associationCancer labMolecular medicineProfessor klaus rajewskyImmune regulationBlood vesselBone marrowBone marrow transplantEpstein barr virusGene editingHemophagocytic lymphohistiocytosisImmune response

Gene editing precisely repairs immune cells

Gene editing precisely repairs immune cells
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Elijahd lowensteinMax delbrKlaus rajewskyXun liK rajewsky labCancer labProfessor klaus rajewskyImmune regulationScience immunology

Immune Cells Precisely Repaired Through Gene Editing

Immune Cells Precisely Repaired Through Gene Editing
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Klaus rajewskyXun liMax delbrChristine kocksCancer labClinical research centerHelmholtz association max delbrBerlin institute of healthGerman centerCardiovascular researchProfessor klaus rajewskyImmune regulationMolecular medicineHelmholtz associationBerlin institute

Gene editing precisely repairs immune cells

Gene editing precisely repairs immune cells
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Klaus rajewskyMax delbrXun liChristine kocksGerman centerClinical research centerBerlin institute of healthCardiovascular researchHelmholtz association max delbrMethod of researchCancer labProfessor klaus rajewskyImmune regulationMolecular medicineHelmholtz associationBerlin institute

Novel Models to Study Multiple Myeloma Disease

Novel Models to Study Multiple Myeloma Disease
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Max delbrMartin janzKlaus rajewskyWiebke winklerHelmholtz association max delbrCardiovascular researchBiology of malignant lymphomas labBerlin institute of healthGerman centerClinical research centerProfessor klaus rajewskyMalignant lymphomas labMolecular medicineHelmholtz associationBerlin institute