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Largest Study of Psychedelic Drugs and How They Affect Brain Chemistry

Largest ever psychedelics study maps changes of conscious awareness to neurotransmitter systems

Applying machine learning to a database of testimonials uncovers how drug-induced changes in subjective awareness are mechanistically rooted in the human brain Psychedelics are now a rapidly growing area of neuroscience and clinical research, one that may produce much-needed new therapies for disorders such as depression and schizophrenia. Yet there is still a lot to know about how these drug agents alter states of consciousness. In the world’s largest study on psychedelics and the brain, a team of researchers from The Neuro (Montreal Neurological Institute-Hospital) and Department of Biomedical Engineering of McGill University, the Broad Institute at Harvard/MIT, SUNY Downstate Health Sciences University, and Mila – Quebec Artificial Intelligence Institute have shown how drug-induced changes in subjective awareness are anatomically rooted in specific neurotransmitter receptor systems. The researchers gathered 6,850 testimonials from people who took a range of 27 different psychede

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