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The primary cilium, an antenna-like subcellular structure ( organelle ) protruding from the outside of many types of vertebrate cells, has an important but previously overlooked role in guiding the growth of lymphatic vessels, shows a new study. The authors show for the first time that mouse and human lymphatic endothelial cells (LECs) - which make up the inner and outer lining of lymphatic vessels - use primary cilia. They find that LEC primary cilia may direct the growth of a functional lymphatic network, not only during prenatal development, but also throughout life during inflammation and wound healing and in response to cancer. They show that mice in which the formation of primary cilia in LECs is prevented develop lymphatic vessels that are locally overgrown, suggesting that signals received by primary cilia may guide proper lymphatic vessel growth patterns. These results, published today in the open access journal
A tour around Kampala City unearthes rich history
Saturday April 24 2021
Summary
How much do you know about your city? Have you ever imagined the rich history that lies behind the existence of each of Kampala’s landmark features? Are you aware that you do not need to spend days or break the bank to tour around these places? Gabriel Buule takes us on a trip around Kampala City.
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It is 10:40am and I am finalising plans to set off to coordinate a trip around Kampala City, organised by Lydia Odaga, the travel consultant of American Travel Bureau.
In the parking lot of National Theatre building, where we are set to depart from, is a sight-seeing bus and all the occupants are excited about touring and learning about the history of Kampala’s best landmarks and attractions.