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VIDEO: Using newly developed software, researchers digitally merged microscopic images of hundreds of zebrafish embryos. This enabled them to identify patterns in how primordial germ cells behave in the absence of. view more
Credit: Gross-Thebing, Truszkowski, Tenbrinck et al. Sci Adv 2020;6: eabc5546/CC BY-NC
Whenever an organism develops and forms organs, a tumour creates metastases or the immune system becomes active in inflammation, cells migrate within the body. As they do, they interact with surrounding tissues which influence their function. The migrating cells react to biochemical signals, as well as to biophysical properties of their environment, for example whether a tissue is soft or stiff. Gaining detailed knowledge about such processes provides scientists with a basis for understanding medical conditions and developing treatment approaches.