In The Family Man 2, Manoj Bajpayee returns as Srikant Tiwari along with Priyamani Raj, Sharib Hashmi, Seema Biswas, Darshan Kumar, Sharad Kelkar, Sunny Hinduja and Shreya Dhanwanthary in pivotal roles. South actress Samantha Akkineni marks her digital debut as antagonist of the show named Raji.