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AB Science SA (Euronext - FR0010557264 - AB) today announces publication of a peer-reviewed article titled ‘ Masitinib is a broad coronavirus 3CL inhibitor that effectively blocks replication of SARS-CoV-2 in the journal Science [1]. The article reports on research that identifies masitinib as a broad antiviral agent capable of treating SARS-CoV-2 (the virus that causes COVID-19), including demonstration of in vivo activity in mice, with efficacy maintained, in vitro, against SARS-CoV-2 variants of concern. This article and its accompanying online supplemental material are accessible online from the journal website: https://science.sciencemag.org/lookup/doi/10.1126/science.abg5827 Research led by Professor Savas Tay and Dr. Nir Drayman from the Pritzker School for Molecular Engineering (University of Chicago, USA) screened a library of 1,900 clinically safe drugs and identified masitinib as the most potent inhibitor of the main target responsible for virus reproduction,

France generalUnited statesArthur rouillAlain moussySavas tayKate barrettePritzker school for molecular engineeringUniversity of chicagoProfessor savas tayNir draymanPritzker schoolMolecular engineeringYear journal impact factorEuronext parisஒன்றுபட்டது மாநிலங்களில்சவாஸ் தாய்