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3.3 (4) The overall cost of disease-modifying therapies for multiple sclerosis (MS) in the U.S. remained stable from 2018 to 2020, according to pharmacy and medical claims data from Prime Therapeutics’ insured members. This stabilization derived from a balance between a reduction in Copaxone (glatiramer acetate injection) use due to the arrival of its generics, and an increase in the use of Ocrevus (ocrelizumab). Generics are nearly identical versions of an original branded medication, typically sold at lower prices. A national pharmacy benefit manager, Prime analyzes real-world medication use pattern changes to negotiate treatment prices and/or rebates with therapy manufacturers and to create lists of medications that health insurance companies, such as those in the Blue Cross Blue Shield Association, will pay.

Genentech ocrevusCatherine starnerMarta figueiredoSarah taylorUniversity of lisbonBlue cross shield associationBiomedical sciencesPrime therapeuticSclerosis disease modifying drugsNew start trendsCommercially insured membersManaged care pharmacy virtual annual meetingBlue plansTeva pharmaceutical copaxoneMolecular biologyUniversidade nova de lisboa