1. In two randomized, noninferiority trials, low-dose calcium in pregnant women with low dietary calcium intake was noninferior to high-dose supplementation in reducing the risk of pre-eclampsia. 2. Low-dose calcium was noninferior to high-dose calcium in reducing the risk of live preterm birth in the trial in India but not in Tanzania. Evidence Rating Level:
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Results showed a 12% incidence of HCV in pregnancy with a preterm birth rate nearly double the national average, although no statistically significant difference in preterm birth rates was observed between HCV-positive and HCV-negative patients.