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Audience Q&A: Best Practices in Managing HER2-Amplified CRC

Fielding questions from the audience, expert oncologists discuss clinical trials, molecular testing, and early-stage disease in the context of HER2-amplified colorectal cancer.

Positive colorectal cancerNovel approachesBest practicesColorectal cancerMetastatic crcColon cancerRectal cancerHer2 positiveTrastuzumab deruxtecanT dxdMolecular testingBiomarker testingMountaineer 3Breakwater trialCirculate usBraf v600e

Real-World Use of HER2-Directed Therapies in Colorectal Cancers

Expert perspectives on the real-world use of HER2-directed therapies in patients with HER2-amplified colorectal cancer.

Positive colorectal cancerNovel approachesWorld useDirected therapiesColorectal cancersColorectal cancerMetastatic crcColon cancerRectal cancerHer2 positiveTrastuzumab deruxtecanT dxdNccn guidelinesTreatment guidelinesTreatment selectionTreatment sequencing

Evolutions in the HER2-Amplified CRC Treatment Landscape

Looking toward the future management of HER2-amplified colorectal cancer, panelists reflect on ongoing clinical trials and evolving treatment strategies.

Positive colorectal cancerNovel approachesColorectal cancerMetastatic crcColon cancerRectal cancerHer2 positiveTrastuzumab deruxtecanT dxdDestiny crc02Mountaineer 3Adjuvant therapyAdjuvant treatment

Treatment Algorithm for Metastatic Colorectal Cancer

Broadening their conversation, expert oncologists define the treatment algorithm for patients diagnosed with colorectal cancer.

Positive colorectal cancerNovel approachesMetastatic colorectalColorectal cancerMetastatic crcColon cancerRectal cancerHer2 positiveEgfr therapyEgfr inhibitorParadigm trialMolecular testingBiomarker testingNext generation sequencingIhc testingImmunohistochemistry test

HER2-Amplified Colorectal Cancer: Clinical Trial Data

A focused discussion on HER2-amplified colorectal cancer and respective clinical trials that inform use of targeted agents in this setting.

Positive colorectal cancerNovel approachesAmplified colorectal cancerClinical trial dataColorectal cancerMetastatic crcColon cancerRectal cancerHer2 positiveTrastuzumab deruxtecanT dxdMountaineer trialMypathway trialDestiny crc01Destiny crc02Interstitial lung disease

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