A thorough comprehension of cellular bio-functionality necessitates knowledge about specific constituents of the cell membrane and, as a result, the structure and organization of protein complexes, as well as tools for high-resolution investigations.
This article focuses on different aspects of cryo-EM, including its advantages and disadvantages, applications, the difference between cryo-EM and electron microscopy (EM) techniques, along with recent studies involving cryo-EM technology.