According to Ayurvedic expert Dr. Rekha Radhamony, certain individuals should avoid consuming ghee. Those with chronic indigestion, stomach issues like IBS-D, or fevers should steer clear of ghee. Pregnant women, especially those overweight or obese, need to be cautious with ghee consumption. Additionally, individuals with liver and spleen diseases such as cirrhosis, hepatomegaly, or hepatitis should also avoid ghee. Dr. Radhamony emphasizes the importance of recognizing that what may be generally considered healthy may not always be suitable for everyone.