Background: New technologies developed to improve survival outcomes for glioblastoma (GBM) continue to have limited success. Recently, image-guided dose painting (DP) radiotherapy has emerged as a promising strategy to increase local control rates. In this study, we evaluate the practical application of a multiparametric MRI model of glioma infiltration for DP radiotherapy in GBM by measuring its conformity, feasibility, and expected clinical benefits against standard of care treatment. Methods: Maps of tumor probability were generated from perfusion/diffusion MRI data from 17 GBM patients via a previously developed model of GBM infiltration. Prescriptions for DP were linearly derived from tumor probability maps and used to develop dose optimized treatment plans. Conformity of DP plans to dose prescriptions was measured via a quality factor. Feasibility of DP plans was evaluated by dose metrics to target volumes and critical brain structures. Expected clinical benefit of DP plans was a
MAYOR RELEASES PRELIMINARY FY24 BUDGET: New York City Mayor Eric Adams released on Jan. 12 the City’s balanced $102.7 billion Preliminary Budget for Fiscal Year 2024 (FY24). The budget reflects the mayor’s ongoing commitment to promoting an equitable recovery by making investments in affordable housing, keeping city streets clean, ensuring the safety of communities, and
Light Rail Selected for New York s Interborough Express Project railwayage.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from railwayage.com Daily Mail and Mail on Sunday newspapers.