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 E-Mail IMAGE: Senior author and Princess Margaret Scientist Dr. Marianne Koritzinsky s research reveals the potential of targeted therapies to exploit unique metabolic features of pancreatic cancer cells. view more  Credit: Visual Services, UHN (Toronto, Friday, May 7, 2021) Probing the unique biology of human pancreatic cancer cells in a laboratory has yielded unexpected insights of a weakness that can be used against the cells to kill them. Led by Princess Margaret Cancer Centre (PM) Scientist Dr. Marianne Koritzinsky, researchers showed that about half of patient-derived pancreatic cancer cell lines are highly dependent or addicted to the protein peroxiredoxin 4 (PRDX4), as a result of the altered metabolic state of the cancer cell.

United statesAlexandra radkewyczMarianne koritzinskyPionyr immunotherapeuticsBradlyg woutersDavid hedleyJason moffatPaulc boutrosUniversity health networkScientific advisory boards of biosymetrics incMichener institute for educationTerry fox foundation research instituteSenior public affairs advisorUniversity of torontoAmerican association for the advancement of scienceInstitute of medical science