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PFS Benefit Observed With Tucatinib Plus T-DM1 in Previously Treated HER2+ Metastatic Breast Cancer

The addition of tucatinib to ado-trastuzumab emtansine (T-DM1) significantly improved progression-free survival vs placebo plus T-DM1 in patients with previously treated HER2-positive metastatic breast cancer, including those with brain metastases.

United statesSan antonioGenentech rocheAstra zenecaEli lillyAlliance foundationGreenwich life sciences incPhoenix molecular designs ltdAntonio breast cancer symposiumPhoenix molecular designsQuantum leapTucatinib plust dm1T dm1Ado trastuzumab emtansinePhase 3 her2climb 02 trialSan antonio breast cancer symposium

Subgroup analysis of trastuzumab deruxtecan reveals encouraging results in controlling stable brain metastases

SABCS: Subgroup analysis of trastuzumab deruxtecan (T-DXd) shows ‘encouraging’ results in controlling stable brain metastases in HER2-positive

United statesSan antonioSara hurvitzAmgen arqule arvinas astrazenecaAstra zenecaDaiichi sankyoRoche genentech seattleHutchinson medipharma immunogen immunomedicsGenentech rocheSerono fochon fujifilmAbbvie acerta pharmaLilly merck mersana novartisJonsson comprehensive cancer centerBsc of health interactionsPhoenix molecular designs ltdRadius health

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