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ACE Inhibitors/ARBs Appear On Par With Beta-blockers After Aortic Dissection

March 08, 2021 Over the long term, patients who survive an aortic dissection appear to do just as well treated with either beta-blockers or ACE inhibitors/ARBs rather than other antihypertensive drugs, a retrospective analysis suggests. Compared with other drug classes, beta-blockers and ACE inhibitors/ARBs each were associated with lower risks of all-cause hospital readmission and all-cause mortality over a span of up to 12 years, according to researchers led by Shao-Wei Chen, MD, PhD (Linkou Medical Center, Chang Gung University, Taoyuan City, Taiwan). There were no differences for any outcomes which also included death due to aortic aneurysm or dissection, later aortic operation, major adverse cardiac and cerebrovascular events, and new-onset dialysis when those two medication groups were compared with each other.

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