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For at least 20 years, the Skeptical Cardiologist has been trying to communicate the current paradigm of coronary heart disease to his patients.
My job has been to translate the physician/scientific description of atherosclerosis: what happens to the arteries in the heart over time, how this results in heart attacks and angina, and what we can do to prevent symptoms, heart attacks, and death.
This description, written 8 years ago in a
Circulation editorial by Michael B. Rothberg, MD, of the Cleveland Clinic, is still a good scientific summary of the process of atherosclerosis: [W]e know that the interactions between dietary fat, serum cholesterol, and arterial endothelium are complex and dynamic. Although high-grade stenoses can cause chronic angina, most cardiac events occur at lesions that appeared mild on previous angiography. These plaques contain a lipid-rich core covered by a thin fibromatous cap. Inflammatory cells (eg, macrophages and mast cells) wi
2020 Wrap-up: COVID-19 s Effects on Cardiology
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NETs a Possible Therapeutic Target for COVID-19 Thrombosis?
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