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Early Improvement in Prurigo Nodularis With IL-31 Antagonist Maintained at 1 Year

Itch, sleep disturbance, lesion healing, quality of life improved substantially in most patients

United statesShawng kwatraAndrew blauveltCharles bankheadOregon medical research centerJohns hopkins itch centerAmerican academy of dermatologyAmerican academyInvestigator global assessmentDermatology life quality indexPeak pruritus numerical rating scaleMedpage today

Nemolizumab Under Review for Prurigo Nodularis, Atopic Dermatitis

Nemolizumab is a humanized monoclonal antibody that antagonizes IL-31 receptor alpha, blocking the signaling of IL-31.

Baldo scassellati sforzoliniDrug administrationBiologics license applicationsPeak pruritus numerical rating scaleEczema areaSeverity index

Study Demonstrates Efficacy, Safety of Topical PF-07038124 for Eczema, Psoriasis

These new data highlight the importance of larger trials to evaluate the persistence of this treatment’s efficacy and safety seen here.

San diegoUnited statesLawrencef eichenfieldUc san diego school of medicineRady childrenHospital san diegoEczema areaSeverity indexGlobal assessmentPeak pruritus numerical rating scalePsoriasis areaAtopic dermatitisPf 07038124

Aldeyra Therapeutics Announces Statistically and Clinically Significant Improvement from Baseline in Phase 2 Clinical Trial of ADX‑629 in Patients with Atopic Dermatitis

Statistically significant improvement from baseline observed in investigator-assessed Eczema Area and Severity Index and Investigator Global Assessment EASI 75% improvement threshold observed.

United statesMatthew zirwasSecurities exchangeAldeyra therapeutics incExchange commissionBexley dermatology researchAldeyra therapeuticsPrincipal investigatorEczema areaSeverity indexInvestigator global assessmentPatient oriented eczema measurePeak pruritus numerical rating scaleHamilton depression rating scaleBeck anxiety inventoryConference call

Aldeyra Therapeutics Announces Statistically and Clinically Significant Improvement from Baseline in Phase 2 Clinical Trial of ADX?629 in Patients with Atopic Dermatitis

Aldeyra Therapeutics Announces Statistically and Clinically Significant Improvement from Baseline in Phase 2 Clinical Trial of ADX?629 in Patients with Atopic Dermatitis
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United statesMatthew zirwasAldeyra therapeutics incBexley dermatology researchSecurities exchangeExchange commissionConference callTherapeutics announces statisticallyClinically significant improvementPrincipal investigatorEczema areaSeverity indexInvestigator global assessmentPatient oriented eczema measurePeak pruritus numerical rating scaleHamilton depression rating scale