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Mitochondrial DNA mutations can reduce death risk in people with bowel cancer
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Mutaciones en el ADN ignoradas podrían tener gran impacto en la supervivencia de los pacientes con cáncer de intestino
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Mutations in overlooked DNA could have profound impact on survival for bowel cancer patients
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Overlooked DNA mutations ‘may increase bowel cancer patients’ survival chances’
The findings are published in the journal Nature Metabolism (Lauren Hurley/PA)
UK scientists have identified a group of mutations in overlooked DNA in tumour cells that may increase the chances of survival for people with bowel cancer.
These mutations are present in the DNA in mitochondria – often known as “powerhouses” of cells because these tiny structures help turn food into energy.
While it is known that mitochondrial mutations can be found in cancer cells, there has been little research into what they do.
In a study funded by Cancer Research UK, the researchers found that patients with colorectal cancer – a common form of bowel cancer – who had these mutations had up to 93% decreased risk of death from their cancer.