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Breakthrough drug halts lung cancer and brain metastases

D'Or Institute for Research and Education (IDOR) played an important role in the phase III LIBRETTO-431 multicenter study, which evaluated the efficacy and safety of selpercatinib compared to control treatment, which consisted of platinum-based chemotherapy associated or not with pembrolizumab (immune checkpoint inhibitor) in non-small cell lung cancer (NSCLC).

Paulo state cancer institute icespDor institute for researchPaulo state cancer instituteNew england journalMilena perez makPaulo state cancerLung cancerNon small cell lung cancerSmall cell lung cancerBrain metastases

Evaluating selpercatinib for the treatment of non-small cell lung cancer

Evaluating selpercatinib for the treatment of non-small cell lung cancer
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Caicun zhouDor institute for researchPaulo state cancer institute icespNew england journalMilena perez makD or institutePaulo state cancer instituteFirst line selpercatinib

IDOR Evaluates Selpercatinib in Non-Small Cell Lung Cancer Study

IDOR Evaluates Selpercatinib in Non-Small Cell Lung Cancer Study
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Dor institute for researchPaulo state cancer institute icespD or instituteNew england journalMilena perez makPaulo state cancer institute

Researchers discover mechanism underlying the development and intensification of cancer treatment-related pain

A combination of chemotherapy and drugs that stimulate the immune system to combat cancer is increasingly used to control progression of the disease in patients.

Alexandre maganinMattar cunhaCarlos wagner wanderleyThiago mattar cunhaQueiroz cunhaPaulo ribeirEmily hendersonCancer immunology researchResearch on inflammatory diseasesPreto medical schoolPaulo state cancer instituteDissemination centerInflammatory diseasesAlbert einstein jewish hospitalCancer immunologyDiscovery industry focus

Mechanism Identified to Intensify Cancer Treatment Pain

Mechanism Identified to Intensify Cancer Treatment Pain
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Alexandre maganinMattar cunhaCarlos wagner wanderleyThiago mattar cunhaQueiroz cunhaPaulo ribeirCancer immunology researchResearch on inflammatory diseasesPreto medical schoolPaulo state cancer institutePaulo research foundationDissemination centerInflammatory diseasesAlbert einstein jewish hospitalCancer immunologyFernando de queiroz cunha