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Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC).

A type of allergy medicine might help treat l

<p style="text-align:justify">Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of <em>non-small cell lung cancer (</em>NSCLC)<em>. </em>&nbsp;And in an early parallel study in humans, combining immunotherapy with dupilumab<em>&mdash;</em>an&nbsp;<a href="https://www.frontiersin.org/articles/10.3389/fimmu.2018.00888/full" target=" blank">Interleukin-4</a>&nbsp;(IL-4) receptor-blocking antibody widely used for treating allergies and asthma<em>&mdash;</em>boosted patients&#39; immune systems, with one out of the six experiencing significant tumor reduction.&nbsp;&nbsp;The findings were described in the December 6 issue of<em> Nature.</em></p>

We had barely got to the beach when there come the Germans – Islander (99) tells story of Occupation escape bid for first time

AN Islander who is soon to turn 100 has shared the never-before-told story of his attempt to steal a boat and join the D-Day landings during the Occupation. Born on 12 May 1923 in Brighton Road, Richard Ahier is due to celebrate his centenary three d.

Society for Immunotherapy of Cancer Forward Fund Announces Recipients of 2021 Postdoctoral Cancer Immunotherapy Fellowships and Awards

Society for Immunotherapy of Cancer Forward Fund Announces Recipients of 2021 Postdoctoral Cancer Immunotherapy Fellowships and Awards
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