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Exercise spurs neuron growth and rewires the brain, helping mice forget traumatic and addictive memories

Researchers have found that increased neuron formation and the subsequent rewiring of neural circuits in the hippocampus through exercise or genetic manipulation helps mice forget traumatic or drug-associated memories. The findings could offer a new approach to treating mental health conditions like post-traumatic stress disorder or drug addiction.

Risako fujikawaAdam ramsaranPaul franklandKyushu university faculty of pharmaceutical sciencesUniversity of torontoAssistant professor risako fujikawaKyushu universityPharmaceutical sciencesProfessor paul frankland

Study shows exercise spurs neuron growth and rewires the brain, helping mice forget traumatic and addictive memories

Researchers from the University of Toronto, Canada, and Kyushu University, Japan, have found that increased neuron formation and the subsequent rewiring of neural circuits in the hippocampus through exercise or genetic manipulation helps mice forget traumatic or drug-associated memories. The findings, reported on May 8 in Molecular Psychiatry, could offer a new approach to treating mental health conditions like post-traumatic stress disorder (PTSD) or drug addiction.

Risako fujikawaAdam ramsaranPaul franklandUniversity of torontoKyushu university faculty of pharmaceutical sciencesKyushu universitySick childrenMolecular psychiatryAssistant professor risako fujikawaPharmaceutical sciencesProfessor paul frankland

Rethinking forgetfulness: The brain s strategic erasure as a learning tool

Rethinking forgetfulness: the brain's strategic erasure as a learning and adaptive tool for enhanced memory recall and decision-making.

Adrian ephraimPaul franklandDepartment of psychologyUniversity of torontoInstitute of neuroscience at trinity college dublinNature reviews neuroscienceAssociate professorTrinity college dublinNature reviewsDecay theoryAlzheimers diseaseFirstrand perspectivesNeurological disorderUsiness newsSouth africa

Study explores the emergence of predictive models in the hippocampus

Study explores the emergence of predictive models in the hippocampus
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Adammp millerPaul franklandSciencex networkUniversity of torontoSick children

Researchers may have identified a molecular cause for memory changes in early childhood

How do our brains become capable of creating specific memories? In one of the first preclinical studies to examine memory development in youth, a research team at The Hospital for Sick Children (SickKids) may have identified a molecular cause for memory changes in early childhood.

Sheena josselynPaul franklandAdam ramsaranAlexander dityatevMegan craigUniversity of torontoFrankland labNeurosciences mental healthGerman centerCanada researchSick childrenSenior scientistsMental healthCanada research chairMolecular neuroplasticityNeurodegenerative diseases