Deep brain stimulation (DBS) to the superolateral branch of the medial forebrain bundle (MFB), which is linked to reward and motivation, revealed metabolic brain changes over 12 months post-DBS implantation, making it a strong potential therapy for treatment-resistant depression according to researchers at UTHealth Houston.
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Newly discovered brain pattern could improve the diagnosis of mental health disorders
A pattern in how the brain breaks down tryptophan, a common amino acid consumed through food, was discovered by researchers at The University of Texas Health Science Center at Houston (UTHealth).
The finding, which could help physicians more accurately diagnose and treat several major mental health disorders, was recently published in
Tryptophan can be metabolized to either a route where serotonin is produced, or to the kynurenine pathway. The research shows that people with mood disorders and schizophrenia not only have decreased levels of tryptophan overall, but the tryptophan they do have is being broken down more often in the kynurenine pathway, shifting away from the production of serotonin, the chemical made from tryptophan that is thought to regulate anxiety and improve mood.
Brain pattern that improve mental health diagnosis austinglobe.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from austinglobe.com Daily Mail and Mail on Sunday newspapers.
Researchers discover brain pattern that could improve mental health disorder diagnosis ANI | Updated: Dec 17, 2020 23:39 IST
Washington [US], December 17 (ANI): A pattern in how the brain breaks down tryptophan, a common amino acid consumed through food, was discovered by researchers at The University of Texas Health Science Center at Houston (UTHealth).
The finding, which could help physicians more accurately diagnose and treat several major mental health disorders, was recently published in Molecular Psychiatry. Tryptophan can be metabolized to either a route where serotonin is produced, or to the kynurenine pathway, said Brisa Fernandes, MD, MSc, PhD, a postdoctoral research fellow with the Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences at McGovern Medical School at UTHealth and co-senior author of the paper.