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An appellant's burden on appeal is never easy but it is particularly difficult when the questions at issue are based on factual evidence.  The appellate judiciary is loathe (generally).

United statesAventis pharma deutschland gmbPathan ejazSchett georgMankind pharma ltdSandoz zydus pharmaceuticals united states incAurobindo pharma united states incMacleods pharmaceuticals ltdApotex incSandoz incHetero united states incAmgen incBettcher indus incAurobindo pharma ltdReddy laboratories ltdSupreme court graham