A new Particle and Particle Systems Characterization study compared the properties of 20 nanometer and 35 nanometer spherical AuNPs, functionalized with a specific thiol-modified oligonucleotide, to develop an improved Au-nanoprobe for the detection of single nucleotide polymorphism (SNP) for lactose intolerance.
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New genome editing technology could pave way for non-viral delivery systems
Researchers from Peter the Great St.Petersburg Polytechnic University (SPbPU) in collaboration with colleagues from Belgium take a step in the development of genome editing technology.
Currently, it is possible to deliver genetic material of different sizes and structures to organs and tissues. This is the key to eliminating DNA defects and treating more patients.
The project is guided by Professor Gleb Sukhorukov and supported by the Russian Science Foundation. Research results were published in
Particle & Particle Systems Characterization journal.
An international research group developed a polymer carrier with a number of unique properties, several types of genetic material can be loaded in its structure. In particular, the scientists managed to load genetic material of various sizes and structures into universal containers . From small interfering RNAs (siRNAs) to messenger RNAs (mRNAs). The effici