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EVEREST-1 Trial Seeks to Bring HLA-A*02-directed CAR T to Patients With Solid Tumors

The upcoming phase 1/2 EVEREST-1 trial, where the novel CAR T-cell therapy A2B530 will be evaluated in patients with solid tumors, aims to push progress for one-and-done engineered therapies in this space.

United statesNew yorkDianem simeonePancreatic cancer centerPerlmutter cancer centerTmodt cellEverest 1 trialHlaa 02 directed cart cell therapySolid tumors

Dr Simeone on the EVEREST-1 Trial Evaluating A2B530 in Solid Tumors

Diane M. Simeone, MD, discusses the phase 1/2 EVEREST-1 trial evaluating the autologous CAR T-cell therapy A2B530 in patients with solid tumors.

United statesDianem simeonePerlmutter cancer centerGrossman school of medicineTranslational researchDepartment of pathologyDepartment of surgeryPancreatic cancer centerIsaac perlmutter professorOnclive tv

Chemo Alters Immune Cells in Pancreatic Cancer

Chemo Alters Immune Cells in Pancreatic Cancer
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New yorkUnited statesNina beriCynthia loomisSurajit dharaLidong wangCristina hajduDespoina kalfakakouDiane simeoneAmanda lundEnde zhaoDaniel weissingerIgor dolgalevGregor werbaXiaohong jingEmily kawaler

Chemotherapy affects immune cell landscape in pancreatic cancer: Study

According to a new study, chemotherapy affects a patient s immune system s ability to target pancreatic cancers.

Diane simeoneAristotelis tsirigosPancreatic cancer centerNature communicationsLangone healthDepartment of surgeryLangone division of precision medicineGrossman school of medicineDepartment of pathologyPerlmutter cancer centerIsaac perlmutter professorPancreatic cancerEws india

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

Diane simeoneAristotelis tsirigosEmily hendersonPancreatic cancer centerCancer research industryNature communicationsLangone healthDepartment of surgeryLangone division of precision medicineCancer researchGrossman school of medicineDepartment of pathologyPerlmutter cancer centerResearch industry focusIsaac perlmutter professorPancreatic cancer

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