Former mayor and CEO of Oscorp, Norman Osborn, mentioned the G-Serum which could have ties to the Goblin Serum which could transform him to Green Goblin.
If there was still any question about whether Insomniac Games was done with making Spider-Man games, the end of PlayStation 5-exclusive Marvel’s Spider-Man 2 makes it clear the studio still has a lot of stories to tell in that universe. Between post-credits cutscenes and new interview teases, it’s clear Insomniac has big plans for Spider-Man 3, and we already have plenty of clues about what it will focus on.