Study in healthy humans showed that modest calorie reduction, rather than specific diet, rewires metabolic and immune responses to boost lifespan and health span.
Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear.
A recent study led by the researchers of Yale university confirms the health benefits of moderate calorie restrictions in humans and identifies a key protein that could be harnessed to extend health in humans.