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New anti-amyloid monoclonal antibody drugs for Alzheimer disease have produced encouraging results in targeting the accumulation of amyloid beta plaques; however, questions remain regarding the risk-benefit profile and cost implications.

Olatunji gbadeboIwatsubot lecanemabWolters kluwer health incPhilo danielEarly alzheimerAntibodies directed against amyloidWolters kluwer healthMonth study withOpen label extension phaseConfirm safetySubjects with early alzheimerParallel group studyClinical benefitParticipants with alzheimerEarly symptomatic alzheimerVersus placebo