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Statins Raise Diabetes Risk, but CV Benefit Outweighs It

Large meta-analysis of individual participant data shows dose-dependent type 2 diabetes increase, but vascular benefit is greater.

Christina reithMarie pigeyreDavid preissHertzelc gersteinUniversity of oxfordNuffield department of population healthMcmaster universityHamilton health sciencesCholesterol treatment trialistLancet diabetesNuffield departmentPopulation healthRaise diabetes riskGlucose levels

April Fools Day 2024 to highlight fakes in Oxford museums

Museums in Oxford are set to display a range of fakes this April Fools’ Day.

City ofUnited kingdomOscar wildeJenny haniverPatricia kingoriNuffield department of population healthOxford university museum of natural historyUniversity of oxfordHistory of science museum in oxfordWeston libraryPitt rivers museumAshmolean museumFalsehoods in global healthLondon natural history museumOxford research centreApril fakes day

Presence of Diabetic Retinopathy Worsens Vision-Related Quality of Life

As diabetic retinopathy severity progresses, both vision-related and health-related scales show a significant deterioration in quality of life scores.

Mohammedg zayedUniversity of oxfordNuffield department of population healthShort form healthNational eye instituteUniversity of oxford mohammedg zayedNuffield departmentPopulation healthVisual function questionnaireShort form health survey

Re: Invasive breast cancer and breast cancer death after non-screen detected ductal carcinoma in situ from 1990 to 2018 in England: population based cohort study

Re: Invasive breast cancer and breast cancer death after non-screen detected ductal carcinoma in situ from 1990 to 2018 in England: population based cohort study
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United kingdomNuffield department of population healthBreast cancerPopulation health

Invasive breast cancer and breast cancer death after non-screen detected ductal carcinoma in situ from 1990 to 2018 in England: population based cohort study

Objectives To evaluate the long term risks of invasive breast cancer and death related to breast cancer after non-screen detected ductal carcinoma in situ. Risks for women in the general population and for women diagnosed with ductal carcinoma in situ via the screening programme were compared. Design Population based cohort study. Setting Data from the National Disease Registration Service. Participants All 27 543 women in England who were diagnosed with ductal carcinoma in situ, outside the NHS breast screening programme, during 1990 to 2018. Main outcome measures Incident invasive breast cancer and death caused by breast cancer. Results By 31 December 2018, 3651 women with non-screen detected ductal carcinoma in situ had developed invasive breast cancer, more than four times higher than expected from national cancer incidence rates (ratio of observed to expected rate was 4.21 (95% conference interval 4.07 to 4.35)). The ratio of observed to expected rate of developing invasive

United kingdomUnited statesDavid dodwellHilary stobartGurdeeps mannuSarahc darbyJohn broggioMairead mackenzieUniversity of oxfordCancer research united kingdomDigital data access request serviceCancer research united kingdom clinician scientist fellowshipNational health serviceResearch ethics committeeNational disease registration servicePublic health england