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Novel approach uses ionic liquids for diverse aptamer applications

Novel approach uses ionic liquids for diverse aptamer applications
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The BRCA2 R2645G variant increases DNA binding and induces hyper-recombination

BRCA2 tumor suppressor protein ensures genome integrity by mediating DNA repair via homologous recombination (HR). This function is executed in part by its canonical DNA binding domain located at the C-terminus (BRCA2CTD), the only folded domain of the protein. Most germline pathogenic missense variants are located in this highly conserved region which binds to single-stranded

Proteins with alpha helices alone and beta sheets alone? - Information

Proteins with alpha helices alone and beta sheets alone? - Information
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