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Streptococcus pneumoniae (S. pneumoniae), remains a major cause of mortality and morbidity worldwide. The objective of this study was to determine the trends of invasive pneumococcal diseases (IPD) in adult and elderly population in Casablanca (Morocco) before and after introduction of pneumococcal conjugate vaccine (PCV) by determining the distribution of pneumococcal serotypes and antibiotic resistance profile of isolated strains. The proposed study is a retrospective laboratory-based surveillance of IPD in hospitalized adult (15–59 years old) and elderly (≥ 60 years old) patients in Ibn Rochd University Hospital Centre from 2007 to 2019 (13 years). All the 250 non-duplicate clinical invasive isolates from adult and elderly patients, confirmed as S. pneumoniae according to the laboratory standard identification procedures, are included in this study. A significant decrease of the overall incidence in IPD was observed only in adults from 0.

Grand casablancaRegion de chaouia ouardighaUnited kingdomTanger téuanMarcy letoileKingdom of moroccoLaboratory standards instituteCenters for diseaseStaten serum instituteStatens serum instituteEuropean committee on antimicrobial susceptibility testingHigh councilNational centreSerum instituteDisease controlEuropean committee