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The neutralizing activity of a panel of 482 human monoclonal antibodies against Omicron BA 4 and BA 5

Researchers demonstrated differential utilization of the B cell germlines and SARS-CoV-2 spike protein epitopes by cross-neutralizing antibodies in infected, vaccinated and individuals with hybrid immunity.

Coronavirus disease covid 19Ngiotensin converting enzyme 2B cellCovid 19Immune responseArs cov 2Evere acute respiratoryEvere acute respiratory syndrome

scRNA-seq of SARS-CoV-2 infected lung organoids finds NFKB Inhibitor Alpha increased in infected cells

Researchers develop a genetically modified airway organoid system, which overcomes challenges related to natural variations in ACE2 levels

World health organizationCoronavirus disease covid 19Ngiotensin converting enzyme 2Progenitor cellsIbonucleic acidArs cov 2Evere acute respiratoryEvere acute respiratory syndromeSpike proteinStem cells

Gut microbiota-derived metabolites offer protection against SARS-CoV-2

A new study investigated how the gut microbiome confers immunity to mammalian hosts against SARS-CoV-2 intranasal infection by generating short-chain fatty acids.

Gut microbesCoronavirus disease covid 19Ars cov 2Ngiotensin converting enzyme 2Covid 19Fatty acidsFlow cytometryEvere acute respiratoryEvere acute respiratory syndromeShort chain fatty acidsSpike protein

Further SARS-CoV-2 variants, and intermittent epidemics may become the new normal

A new study explores the dynamics of the SARS-CoV-2 Omicron and other variants circulating in England.

United statesCity ofUnited kingdomMayboon shutterstockAssessment of communityNature communicationsjournalOmicron epidemicImage creditNorth eastBayesianp splineCoronavirus disease covid 19Ngiotensin converting enzyme 2Covid 19Ars cov 2Evere acute respiratoryEvere acute respiratory syndrome

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

A new study revealed that the replication of the ancestral strain of SARS-CoV-2 is less efficient in nasal epithelial cells (NECs) of children.

Coronavirus disease covid 19Ars cov 2Ngiotensin converting enzyme 2Covid 19Evere acute respiratoryEvere acute respiratory syndrome

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