Molecular Underpinnings of Memory Now Better Understood
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December 10, 2020
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Neuroscientists at Harvard Medical School (HMS) believe they have taken a decisive step in the quest to understand the biology of long-term memory and find ways to intervene when memory deficits occur with age or disease. In an article, “Bidirectional perisomatic inhibitory plasticity of a
Nature, they describe a newly identified mechanism that neurons in the adult mouse hippocampus use to regulate signals they receive from other neurons, in a process that appears critical for memory consolidation and recall.
The study was led by Lynn Yap, HMS graduate student in neurobiology, and Michael Greenberg, PhD, the HMS Nathan Marsh Pusey professor of neurobiology, chair of neurobiology in the Blavatnik Institute at HMS, and study corresponding author.