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The accumulation of metabolic waste is a leading cause of numerous neurological disorders, yet we still have only limited knowledge of how the brain performs self-cleansing. Here we demonstrate that neural networks synchronize individual action potentials to create large-amplitude, rhythmic and self-perpetuating ionic waves in the interstitial fluid of the brain. These waves are a plausible mechanism to explain the correlated potentiation of the glymphatic flow1,2 through the brain parenchyma. Chemogenetic flattening of these high-energy ionic waves largely impeded cerebrospinal fluid infiltration into and clearance of molecules from the brain parenchyma. Notably, synthesized waves generated through transcranial optogenetic stimulation substantially potentiated cerebrospinal fluid-to-interstitial fluid perfusion. Our study demonstrates that neurons serve as master organizers for brain clearance. This fundamental principle introduces a new theoretical framework for the functioning of ma
Transcripts for BBCNEWS Click 20210917 01:53:15 archive.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from archive.org Daily Mail and Mail on Sunday newspapers.
applications, there could be a dark side to this technology. the problem comes when we don t just measure the activity in the brain but we try to directly influence it. that means we could do things like read someone s thoughts or change their perception reality or even make them act against their free will. my biggest worry is mental privacy. you can imagine using them for interrogation, for example. you ask a question, just by the image the person recalls, they can figure out what the person is thinking. technology companies have jumped into neurotech in a big way and it also means that they are very keen on getting their hands on mental data. on neural data. and i think that should be protected. it may sound far fetched but elon musk is already working towards writing to the brain to augment human knowledge and another doctor has taken control of a mouse s mind and is campaigning for ethical frameworks and