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CTX130 Provides Disease Control and Manageable Safety in Advanced ccRCC

The anti-CD70 CAR T-cell therapy CTX130 showed activity and manageable toxicities in advanced renal cell carcinoma.

Texas
United-states
San-diego
California
Houston
Samera-srour
International-metastatic-renal-cell-carcinoma-database-consortium
Division-of-cancer-medicine
University-of-texas-md-anderson-cancer-center
Department-of-stem-cell-transplantation
Cancer-discovery

Overview of Non–Clear Cell RCC

The expert panel gives an overview of non–clear cell renal cell carcinoma, highlighting disease subtypes and treatment approaches.

Advanced-renal-cell-carcinoma
Clear-cell
Renal-cell-carcinoma
Nrcc
Advanced-rcc
Non-clear-cell-rcc
Non-clear-cell-renal-carcinoma
Papillary-rcc
Translocation-renal-cell-carcinoma
Nccrcc

Dr Arner on the Role of SETD2 Loss in Tumor Growth and Metastasis in ccRCC

Emily Arner, PhD, discusses research on the role of SETD2 loss in metastatic clear cell renal cell carcinoma ccRCC.

Emily-arner
Vanderbilt-university-medical-center
Division-of-hematology-oncology
Onclive
Nccrcc
Setd2
Renal-cell-carcinoma
Tumor-microenvironment
Mouse-model

Subcutaneous Nivolumab Provides Clinical Equipoise to Standard IV Dosing in ccRCC

Subcutaneous nivolumab coformulated with rHuPH20 demonstrated noninferiority of PK exposures vs intravenous nivolumab in metastatic ccRCC.

Mexico
New-york
United-states
Saby-george
Jacobs-school-of-medicine
Network-clinical-trials
Roswell-park-comprehensive-cancer-center
University-of-buffalo
Biomedical-sciences
Jacobs-school
South-america
Nivolumab

Adjuvant Pembrolizumab Significantly Prolongs OS vs Placebo in ccRCC

Treatment with adjuvant pembrolizumab significantly improved overall survival vs placebo in patients with clear cell renal cell carcinoma.

Massachusetts
United-states
Boston
Dana-farber-cancer-institute
Bristol-myers-squibb
Nancy-kohlberg
Toni-choueiri
Roche-genentech
Calithera-biosciences
Sanofi-aventis
Astrazeneca
Michaelj-hennessy-associates

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