NMRFAM Co-Directors Awarded P41, Pioneer New Methods
Professors Katie Henzler-Wildman and Chad Rienstra, co-directors of the National Magnetic Resonance Facility at Madison (NMRFAM), have been awarded a P41 grant to pioneer new methods for solid-state NMR. The research is funded by the National Institutes of Health and provides $6.5 million over 5 years.
The project builds on existing NMR technology to extend its reach to the broader scientific community. It includes collaborations between NMRFAM and leading experts in the study of Parkinson s disease, antifungal drug development, blood coagulation, and the function of ion channels and membrane protein transporters.
The P41 focuses on development in three areas: 1) sample preparation that will bridge a gap in current structural biology and enhance understanding of how essential membrane proteins function; 2) instrumentation that improves the sensitivity and resolution of NMR experiments; and 3) algorithms and software to aut