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Influenza A virus causes respiratory disease in many animal species as well as in humans. Due to the high human-animal interface, the monitoring of canine influenza in dogs and the study of the transmission and pathogenicity of canine influenza in animals are important. Eight-week-old beagle dogs (Canis lupus familaris) (n = 13) were used for the intraspecies transmission model. The dogs were inoculated intranasally with 1 ml of 106 EID50 per ml of canine H3N2 influenza virus (A/canine/Thailand/CU-DC5299/2012) (CIV-H3N2). In addition, 4-week-old guinea pigs (Cavia porcellus) (n = 20) were used for the interspecies transmission model. The guinea pigs were inoculated intranasally with 300 µl of 106 EID50 per ml of CIV-H3N2. For the Thai CIV-H3N2 challenged in the dog model, the incoculated and direct contact dogs developed respiratory signs at 2 dpi. The dogs shed the virus in the respiratory tract at 1 dpi and developed an H3-specific antibody again
Running a facility for laboratory animals not only involves caring for thousands of mice, but also requires a sharp eye to identify each animal’s unique personality.
Whenever the conversation turns to animal personalities, National Laboratory Animal Center director-general Genie Chin’s (秦咸靜) face softens and eyes light up, like a parent excited to gush about their many children.
Apart from the independent hamster, many rodents are social creatures, she said.
For example, each of the 20,000 mice breeds has their own distinct personality traits, she said.
Some like to “party,” some are maternal and enjoy raising their young, and others even like to drink alcohol,