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The COVID-19 pandemic led to a stark decline in kidney care that has yet to rebound, a new retrospective study suggested.
Overall healthcare utilization dropped by 43% during the pandemic among Medicare beneficiaries with advanced chronic kidney disease (CKD) compared with the year prior, reported Clarissa Diamantidis, MD, MHS, of Duke University School of Medicine in Durham, North Carolina, and colleagues.
Based on healthcare utilization prior to the pandemic specifically January 2019 through February 2020 these CKD patients were expected to have roughly 2.74 million in-person healthcare visits during the period in which the pandemic hit. But from March through June 2020, this group only actually had about 1.56 million in-person healthcare visits.
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Metformin was both safe and well tolerated in patients with autosomal dominant polycystic kidney disease (ADPKD), the phase II TAME PKD trial found.
The parallel-group, randomized trial of 97 participants found no significant increase in gastrointestinal symptoms over 24 months, according to Ronald Perrone, MD, of Tufts Medical Center in Boston, and colleagues.
As measured by the Gastrointestinal Symptoms Rating Scale (GSRS), patients on metformin also didn t see any gastrointestinal tolerability issues compared with those on placebo. Lactic acidosis and hypoglycemia were not found to be problematic, Perrone said during a presentation of the late-breaking findings at the virtual National Kidney Foundation Spring Clinical Meeting. However, there was no evidence signal for efficacy to slow progression.
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Organ donation and kidney transplants have made an “amazing” recovery from the worst days of the pandemic, a speaker said here, with more than 33,000 kidney transplants performed in 2020.
“There were some parts of the Northeast where there were zero living donor transplants done for weeks,”
Matthew Cooper, MD, director of Kidney and Pancreas Transplantation at Medstar Georgetown Transplant Institute and professor of surgery at Georgetown University School of Medicine, said during a presentation at the virtual National Kidney Foundation Spring Clinical Meetings. “It was amazing how the country regained . the key was getting organs to areas where transplants could happen.”